Primary Identifier | MGI:6507847 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(DMD*)#Spc |
Strain of Origin | STOCK Tg(DMD)72Thoen/J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology generated a deletion of exon 45 of the human DMD in Tg(DMD)72Thoen mice. Two founders were used to establish lines, however the pound symbol (#) is used when line is not specified and/or lines are pooled. The transgene integrated on chromosome 5 in a tail to tail duplication. |