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Allele : Tg(DMD*)#Spc transgene insertion, Melissa J Spencer

Primary Identifier  MGI:6507847 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(DMD*)#Spc
Strain of Origin  STOCK Tg(DMD)72Thoen/J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a deletion of exon 45 of the human DMD in Tg(DMD)72Thoen mice. Two founders were used to establish lines, however the pound symbol (#) is used when line is not specified and/or lines are pooled. The transgene integrated on chromosome 5 in a tail to tail duplication.
  • mutations:
  • Insertion
  • synonyms:
  • hDMD del45,
  • hDMD del45
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele