| Primary Identifier | MGI:6490339 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Matr3 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a C to G change at position 254 (c.254C>G) that results in serine to cysteine substitution at amino acid 85 (p.S85C). These mice also have two silent mutations (c.261T>C, p.F87 and C.264C>T, p.N88) which prevent re-cleavage of the repaired allele and remove an MseI restriction endonuclease site, allowing for genotyping. |
