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Allele : Cpa1<tm1.1Satom> carboxypeptidase A1, pancreatic; targeted mutation 1.1, Miklos Sahin-Toth
Primary Identifier  MGI:6501733 Allele Type  Targeted
Attribute String  Not Specified Gene  Cpa1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 7 was replaced with a floxed neomycin resistance cassette and exon 7 mutated to produced the nucleotide substitution of asparagine with lysine at position 256 (N256K). Cre-mediated recombination removed the selection cassette and allowed for expression of the mutated allele. This mutation is present in human patients with pancreatitis.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • CPA1 N256K,
  • CPA1 N256K
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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