| Primary Identifier | MGI:6510804 | Allele Type | Endonuclease-mediated |
| Gene | Nhlrc2 | Strain of Origin | C57BL/6NCrl |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G-to-T mutation was engineered using crRNA, tracrRNA and an ssODN template with CRISPR/Cas9 technology. The c.442G>T mutation changes aspartic acid codon 148 to a tyrosine codon (p.Asp148Tyr), mimicking a mutation found in FINCA (fibrosis, neurodegeneration, and cerebral angiomatosis) syndrome patients. |
