|  Help  |  About  |  Contact Us

Allele : Nexn<em1Chen> nexilin; endonuclease-mediated mutation 1, Ju Chen

Primary Identifier  MGI:6510879 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s) Gene  Nexn
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A 3 bp region coding for the amino acid residue G645 (equivalent to the human G650) was deleted from the endogenous gene using CRISPR/Cas9 genome editing technology. mRNA levels are normal but protein levels are decreased to 30% of wild-type levels in homozygotes.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Nexn G645del,
  • Nexn<G645delta>,
  • Nexn G645del,
  • Nexn<G645delta>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories