| Primary Identifier | MGI:6511038 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Cmtm6 |
| Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | EUCOMM |
| molecularNote | The L1L2_Pgk_P cassette was inserted at position 114565819 of Chromosome 9 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 114569458. Exon 2 and 3 are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by subsequent flp-mediated recombination to remove the lacZ-neo cassette. |
