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Allele : Scn1b<tm2.2Isom> sodium channel, voltage-gated, type I, beta; targeted mutation 2.2, Lori L Isom

Primary Identifier	MGI:6508110	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Scn1b
Transmission	Germline	Strain of Origin	129X1/SvJ
Is Recombinase	false	Is Wild Type	false

molecularNote

LoxP sites were inserted 190 bp upstream and 220 bp downstream of exon 2. A FRT-flanked neomycin cassette was that was inserted further downstream of exon 2 was subsequently removed via FLP1-mediated recombination in the germline.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Scn1b<flox>,
Scn1b<flox>

earliestPublication:
Chen C, et al. (2007) Floxed allele for conditional inactivation of the voltage-gated sodium channel beta1 subunit Scn1b. Genesis 45(9):547-53

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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