Primary Identifier | MGI:6508395 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lypd8 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Replacement of genomic fragment containing the third and fourth exons of the gene with a loxP-flanked neomycin-resistance gene cassette. Quantitative RT-PCR analysis revealed that Lypd8 expression is significantly reduced in the colon of homozygous mutant mice. |