| Primary Identifier | MGI:6508533 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Bin2 |
| Transmission | Germline | Strain of Origin | (C57BL/6NTac x 129S6/SvEvTac)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site and an frt-flanked neomycin selection cassette was inserted 403 bp upstream of exon 3, and a single loxP site was inserted downstream of exon 3. The neomycin selection cassette was removed via FLP-mediated recombination and exon 3 was removed via Cre-mediated recombination in the germline. Western blot analysis confirmed the complete loss of protein expression in all tested tissues. |
