| Primary Identifier | MGI:6715338 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Fmr1 |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The CGA arginine codon was changed into a CAA nucleotide triplet coding for a glutamine (R138Q; c.413G>A) in exon 5. In addition, a loxP flanked neomycin cassette was inserted downstream of exon 5 and removed via cre-mediated recombination. This is a missense mutation identified in Fragile X syndrome patients. |
