|  Help  |  About  |  Contact Us

Allele : Rock1<tm1.1Bicrq> Rho-associated coiled-coil containing protein kinase 1; targeted mutation 1.1, Cancer Research UK Beatson Institute
Primary Identifier  MGI:6696418 Allele Type  Targeted
Gene  Rock1 Transmission  Germline
Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 27 was replaced with a floxed neomycin resistance cassette and a modified exon 27 with the amino acid substitution of aspartic acid with alanine at position 1113 (D1113A) to make the produced protein caspase-resistant. Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • ROCK1 D1113A,
  • ROCK1nc,
  • ROCK1 D1113A,
  • ROCK1nc
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom