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Allele : Atm<tm2.2Fwa> ataxia telangiectasia mutated; targeted mutation 2.2, Frederick W Alt

Primary Identifier  MGI:6696452 Allele Type  Targeted
Attribute String  Null/knockout Gene  Atm
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  Sequence encoding the core PIKK kinase domain of the protein protein product were floxed by placing a loxP site upstream of exon 57 and floxed neomycin cassette downstream of exon 58. The neomycin cassette was subsequently removed by transient infection of cre recombinase, and exons 57-58 were removed via Cre-mediated recombination in the germline.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Atm<delta>,
  • Atm<delta>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories