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Allele : Gt(ROSA)26Sor<em1(Tor1b)Wtd> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, William T Dauer

Primary Identifier	MGI:6710954	Allele Type	Endonuclease-mediated
Attribute String	Conditional ready, Inserted expressed sequence	Gene	Gt(ROSA)26Sor
Strain of Origin	C57BL/6N	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Extreme genome editing technology knocked-in the Tor1b cDNA that is preceded by a floxed stop cassette into the locus. Tor1b is expressed after cre-mediated deletion of the stop cassette.

mutations:
Insertion

synonyms:
B-OE,
B-OE

earliestPublication:
Li J, et al. (2020) TorsinB overexpression prevents abnormal twisting in DYT1 dystonia mouse models. Elife 9:e54285

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

3 Publication categories

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