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Allele : Tg(Vil1-Lyz1)#Ngao transgene insertion, Nan Gao

Primary Identifier	MGI:6717274	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(Vil1-Lyz1)#Ngao
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

In this transgene construct, the CDS from a mouse lysozyme 1 cDNA was placed between the mouse villin 1 promoter and SV40 polyA signal sequences to drive expression of lysozyme in intestinal epithelial cells. Two separate mouse lines were maintained.

mutations:
Insertion

synonyms:
Villin-Lyz1<TG>,
Villin-Lyz1<TG>

earliestPublication:
Yu S, et al. (2020) Paneth Cell-Derived Lysozyme Defines the Composition of Mucolytic Microbiota and the Inflammatory Tone of the Intestine. Immunity 53(2):398-416.e8

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

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