Primary Identifier | MGI:6717121 | Allele Type | Transgenic |
Attribute String | Recombinase | Gene | Tg(Amelx-icre)#Ppap |
Strain of Origin | C57BL/6 | Is Recombinase | true |
Is Wild Type | false |
molecularNote | The transgene was created by modifying BAC by replacing exon 2 of the mouse Amelx gene with an improved cre recombinase gene (icre). An FRT-flanked kanamycin resistance cassette was removed prior to injection. 4 independent BAC founder lines (854, 863, 872, and 876) were collected. Line 854 and 872 were selected for studies due to a strong ameloblast-specific expression pattern. The pound symbol (#) is used when no line is specified and/or lines are pooled. |