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Allele : Tnfsf10<tm1.1Daav> tumor necrosis factor (ligand) superfamily, member 10; targeted mutation 1.1, Dario Vignali

Primary Identifier  MGI:6835669 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tnfsf10
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted a loxP site upstream of exon 2 and an FRT site, loxP site, 2A sequence, and a truncated (nonfunctional) NGFR reporter gene for cre-mediated deletion downstream of exon 5. FLP-mediated recombination removed the selection cassette inserted downstream of exon 5. NGFR expression is minimal even upon cre-mediated recombination thus cannot be used as intended.
  • mutations:
  • Insertion
  • synonyms:
  • Tnfsf10<L>,
  • Tnfsf10<L>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories