Primary Identifier | MGI:6718624 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Pomc |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Mice with lox sites flanking exon III of the Pomc gene were generated using gene targeting in ES cells. The founders were bred to female mice bearing a germline-expressing Flpe recombinase transgene to obtain germ-line transmission of the floxed Pomc allele and to remove the frt-kanamycin-frt cassette. |