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Allele : Oprm1<tm1.1(cre/ERT2)Dwata> opioid receptor, mu 1; targeted mutation 1.1, Dai Watanabe

Primary Identifier  MGI:6718628 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Oprm1
Transmission  Germline Strain of Origin  C57BL/6NSlc
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A bacterial artificial chromosome (BAC) containing the mouse Oprm1 gene (RP24-112H16) was modified so that the translational stop codon in exon 4 of the Oprm1 gene was replaced by a cassette comprising the T2A sequence, icre/ERT2 gene with stop codon and FRT-flanked neomycin-resistant gene (T2A-iCreERT2-FRT-Neo-FRT). The homologous recombination in the mouse ES cells generated a chimeric mouse which was crossed with CAG-FLPe mice to remove the FRT-flanked neomycin resistance cassette in the offspring.
  • mutations:
  • Insertion
  • synonyms:
  • MOR-CreER,
  • MOR-CreER
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories