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Allele : Doc2b<em1(folA/cre)Guru> double C2, beta; endonuclease-mediated mutation 1, Channabasavaiah Gurumurthy
Primary Identifier  MGI:6718299 Allele Type  Endonuclease-mediated
Attribute String  Inducible, Recombinase Gene  Doc2b
Strain of Origin  C57BL/6J Induced With  trimethoprim
Is Recombinase  true Is Wild Type  false
molecularNote  CRISPR/cas9 endonuclease mediated genome editing is used to introduce P2A-trimethoprim(TMP)-inducible cre (ddCre) cassette immediately before the stop codon of Doc2b gene. Cre recombinase is fused to the destabilizing DHFR (or folA) domain, which can be transiently stabilized by the administration of TMP.
  • mutations:
  • Insertion
  • synonyms:
  • Doc2b<ddCre>,
  • Doc2b<ddCre>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

2 Publication categories





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