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Allele : Hoxa13<tm1.1(cre/ERT2)Mtor> homeobox A13; targeted mutation 1.1, Miguel Torres
Primary Identifier  MGI:6718975 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Hoxa13
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NTac)F1
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  The targeting vector containing Cre-ERT2-FRT-Neo-FRT-LoxP cassette inserted into exon 1 just downstream of the endogenous ATG site of Hoxa13 gene, replacing 1864 base pairs of the coding region spanning exons 1 and 2 was generated from a C57BL/6 BAC (bacterial artificial chromosome) clone (RPCI23:33N14) using homologous recombination. C57BL/6NTac × 129S6/SvEvTac embryonic stem (ES) cells (Taconic) were electroporated with the targeting construct to generate chimera. After germline transmission, the Neo resistance cassette was eliminated by breeding with a Flpe deleter line.
  • mutations:
  • Insertion
  • synonyms:
  • Hoxa13<CreER>,
  • Hoxa13<CreER>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories





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