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Allele : Pfn4<em1Hsc> profilin family, member 4; endonuclease-mediated mutation 1, Hubert Schorle

Primary Identifier  MGI:6718278 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Pfn4
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting of exons 2 through 4 deleted of 5417 bp leading to generation of a 5' truncated nonsense protein. qRT-PCR analysis confirmed the absence of mRNA expression in the testes of homozygous mutant males.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pfn4deltaa,
  • Pfn4deltaa
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories