| Primary Identifier | MGI:6718577 | Allele Type | Targeted |
| Attribute String | Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vector consisting of a CAG promoter, loxP-stop-loxP (LSL) cassette and HA-tagged human VPS35 containing an aspartate to asparagine substitution at amino acid 620 (D620N) was inserted into the locus. The D620N mutation has been identified as a pathogenic mutation for late-onset autosomal dominant Parkinson's disease. |
