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Allele : Igs2<em8(KRT14-icre)Gpt> intergenic site 2; endonuclease-mediated mutation 8, GemPharmatech Co., Ltd

Primary Identifier	MGI:6718926	Allele Type	Endonuclease-mediated
Attribute String	Recombinase	Gene	Igs2
Strain of Origin	C57BL/6JGpt	Is Recombinase	true
Is Wild Type	false

molecularNote

CRISPR-targeting introduced an icre driven by human KRT14 enhancer and promoter into Igs2 H11 docking site.

mutations:
Insertion

synonyms:
keratin14-Cre,
keratin14-Cre,
H11-hKRT14-iCre,
H11<em1Cin(hKRT14-iCre)>,
H11-hKRT14-iCre,
H11<em1Cin(hKRT14-iCre)>

earliestPublication:
Qu H, et al. (2021) Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing. Diabetes 70(5):1170-1184

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

2 Publication categories

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