Primary Identifier | MGI:6719400 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | Not Specified |
Induced With | mifepristone | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A splice acceptor site was inserted immediately before the Dre and the mutated human progesterone receptor (PGR) consisting of the Ru486 responsive mutant hormone-binding domain hPR891 was fused to the N-terminus of Dre sequence followed by a bovine growth hormone (BGH) polyadenylation signal and PGK-Puro selection cassette. The targeting vector was inserted into a Gt(ROSA)26Sor site by homologous recombination in ES cells. |