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Allele : Gt(ROSA)26Sor<tm6(dre/PGR*)Dwi> gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Douglas J Winton
Primary Identifier  MGI:6719400 Allele Type  Targeted
Attribute String  Inducible, Recombinase Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Induced With  mifepristone Is Recombinase  true
Is Wild Type  false
molecularNote  A splice acceptor site was inserted immediately before the Dre and the mutated human progesterone receptor (PGR) consisting of the Ru486 responsive mutant hormone-binding domain hPR891 was fused to the N-terminus of Dre sequence followed by a bovine growth hormone (BGH) polyadenylation signal and PGK-Puro selection cassette. The targeting vector was inserted into a Gt(ROSA)26Sor site by homologous recombination in ES cells.
  • mutations:
  • Insertion
  • synonyms:
  • RDre<Pr>,
  • RDre<Pr>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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Trail: Allele




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