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Allele : Slc12a5<tm2.1Geno> solute carrier family 12, member 5; targeted mutation 2.1, Genoway

Primary Identifier  MGI:6755215 Allele Type  Targeted
Gene  Slc12a5 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  An ACA to GCC change resulting in a threonine to alanine substitution at amino acid 906 (T906A) and an ACC to GCC change resulting in a threonine to alanine substitution at amino acid 1007 (T1007A) were inserted into exons 22 and exon 24, respectively. A loxP-flanked neomycin selection cassette inserted between exon 22 and 23 was removed via cre-mediated recombination.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • KCC2-T906A/T1007A,
  • KCC2-T906A/T1007A
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories