|  Help  |  About  |  Contact Us

Allele : Gt(ROSA)26Sor<tm1(CAG-Yap1*S112A,-EGFP)Rha> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Ralf H Adams

Primary Identifier  MGI:6719207 Allele Type  Targeted
Attribute String  Conditional ready, Constitutively active, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A vector consisting of CAG, loxP-flanked neomycin and STOP cassette, a Yap1 cDNA containing a serine to alanine substitution at amino acid 112 (S112A), FRT flanked IRES-EGFP, and pA was inserted into the locus. The S112A mutation results in a constitutively active Yap1. Expression of the constitutively active product is only achieved following cre mediated recombination.
  • mutations:
  • Insertion
  • synonyms:
  • Yap1<S112A>,
  • Yap-KI,
  • Yap1<S112A>,
  • Rosa26-Yap1<S112A>,
  • Rosa26-Yap1<S112A>,
  • Yap-KI
Quick Links:
 
Quick Links:
 

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories