Primary Identifier | MGI:6719207 | Allele Type | Targeted |
Attribute String | Conditional ready, Constitutively active, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A vector consisting of CAG, loxP-flanked neomycin and STOP cassette, a Yap1 cDNA containing a serine to alanine substitution at amino acid 112 (S112A), FRT flanked IRES-EGFP, and pA was inserted into the locus. The S112A mutation results in a constitutively active Yap1. Expression of the constitutively active product is only achieved following cre mediated recombination. |