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Allele : Tnfsf11<em2Caob> tumor necrosis factor (ligand) superfamily, member 11; endonuclease-mediated mutation 2, Charles A O'Brien

Primary Identifier  MGI:6754164 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Tnfsf11
Strain of Origin  (C57BL/6 x BALB/c)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  Putative proximal enhancer sequence between -1413 and -510 bp upstream of the transcription start site (chr14:78545488 (build GRCm39)) was targeted with sgRNAs (targeting CAAGGTTTATAGGTGTTCTA and CCTCTCTTACGGGAGTCTAT) using CRISPR/Cas9 technology, resulting in a 909 bp deletion.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • eKO,
  • eKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories