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Allele : Tg(Ttr-Proc*)#Wlr transgene insertion, Harmut Weiler

Primary Identifier  MGI:6755161 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ttr-Proc*)#Wlr
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  A cDNA for a mutagenized murine protein C gene where D168F and N173K codon changes (D209F, N214K for pre-pro-peptide) were introduced, was placed in exon 2 in a 3 kb fragment containing the promoter and exons 1 and 2 of the liver-specific transthyretin gene. The mutations create a hyper-activatable form of the enzyme.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • APC<HI>,
  • APC<HI>,
  • mAPC<HI>,
  • mAPC<HI>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories