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Allele : Pcdhga7<em1(IMPC)J> protocadherin gamma subfamily A, 7; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:6727352 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Pcdhga7
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GCAATGGCGCCTGGACAGAG and GGGTGAAGCCCCAAGTTCCC, which resulted in a 2435 bp deletion beginning at Chromosome 18 position 37,847,990 bp and ending after 37,850,424 bp (GRCm39/mm39). This mutation deletes 2435 bp from ENSMUSE00001346069 (exon 1) including the start site but leaves the last 3 nucleotides before the end of the exon, and is predicted to result in a null allele.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories