| Primary Identifier | MGI:6719074 | Allele Type | Endonuclease-mediated |
| Attribute String | Not Specified | Gene | Polg |
| Strain of Origin | FVB/NJ | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 7 was targeted for a G-to-A mutation at alanine codon 449 (GCT), changing it to threonine (ACT) (c.1345G>A, p.Ala449Thr), with sgRNAs and an ssODN template using CRISPR/Cas9 technology. This mutation mimics the most common human recessive mutation p.Ala467Thr. |
