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Allele : Gucy1b2<tm4.1(cre)Mom> guanylate cyclase 1, soluble, beta 2; targeted mutation 4.1, Peter Mombaerts

Primary Identifier  MGI:6719255 Allele Type  Targeted
Attribute String  Recombinase, Reporter Gene  Gucy1b2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  true Is Wild Type  false
molecularNote  Sequence encoding an IRES followed by Cre recombinase with a nuclear localization signal followed by a second IRES and tau-lacZ followed by an FRT-flanked neomycin selection cassette was inserted immediately downstream of the stop codon, leaving the coding sequence intact with tri-cistronic expression resulting in the co-expression of nuclear-localized cre and the tau-lacZ reporter. Flp-mediated excision removed the neomycin selection cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Gucy1b2-IRES-nlsCre-IRES-taulacZ,
  • Gucy1b2-IRES-nlsCre-IRES-taulacZ
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

4 Publication categories