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Allele : Adamts10<em1Jku> ADAM metallopeptidase with thrombospondin type 1 motif 10; endonuclease-mediated mutation 1, John Kuchtey

Primary Identifier  MGI:6783437 Allele Type  Endonuclease-mediated
Gene  Adamts10 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology introduced a glycine to arginine substitution at amino acid 661 (G661R). The G661R mutation was identified in a colony of Beagles with inherited primary open-angle glaucoma.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Adamts10<G661R>,
  • Adamts10<G661R>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories