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Allele : Gt(ROSA)26Sor<tm6(CAG-CHRM3*,-ZsGreen)Jcbr> gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Jens C Bruning
Primary Identifier  MGI:6828737 Allele Type  Targeted
Attribute String  Conditional ready, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct consisting of a CAG promoter, a loxP-flanked neo stop cassette, a rox-flanked stop cassette, and DREADD (Designer Receptors Exclusively Activated by Designer Drugs) receptor hM3Dq, followed by 2A-NLS-ZsGreen and pA signal all inserted into the Gt(ROSA)26Sor locus was used to generate the mouse line by homologous recombination in ES cells. CAG promoter drives expression of hM3Dq and ZsGreen only after Cre and Dre mediated excision of the floxed and roxed stopper elements.
  • mutations:
  • Insertion
  • synonyms:
  • ROSA26lSlrSrhM3Dq,
  • ROSA26lSlrSrhM3Dq
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories





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