Primary Identifier | MGI:6720274 | Allele Type | Endonuclease-mediated |
Attribute String | Conditional ready | Gene | Adamts5 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting construct comprised of 1.5 kb flanking homology arms, floxed exon 3, and a flippase recombination targetâflanked neomycin resistance cassette replaced endogenous Adamts5 sequences by CRISPR/Cas9-mediated homologous recombination in ES cells. |