| Primary Identifier | MGI:6771348 | Allele Type | Targeted |
| Attribute String | Inserted expressed sequence | Gene | Aire |
| Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeting vector is designed to replace exon 1 with a membrane-bound form of ovalbumin consisting of a fusion protein made up of the first 118 residues of the human transferrin receptor (which includes the cytoplasmic tail and signal/anchor domain) linked to residues 139-385 of the chicken ovalbumin gene (OVA), followed by a loxP-flanked neo cassette. Cre-mediated recombination removed the floxed neo cassette. |
