| Primary Identifier | MGI:6728093 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Klhl3 |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G-to-A mutation was introduced into exon 15, changing arginine codon 528 (CGC) to a histidine codon (CAC), and an FRT site flanked puromycin resistance gene cassette was inserted into intron 15. The puro cassette was removed through subsequent flp-mediated recombination. The mutation is found in familial hyperkalemic hypertension (FHHt) patients. |
