Primary Identifier | MGI:6720891 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Foxp2 |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | true | Is Wild Type | false |
molecularNote | The allele was generated by inserting a 2A-cre expression cassette in-frame before the STOP codon of the Foxp2 gene. The targeting vectors generated using BAC clones from the RPCI-23&24 library were electroporated into a 129SVj/B6 hybrid ES cell line (v6.5). The Resulting ES cell clones were used for tetraploid complementation to obtain male heterozygous mice. |