| Primary Identifier | MGI:6723946 | Allele Type | Targeted |
| Attribute String | Conditional ready, Inserted expressed sequence, Reporter | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A construct comprising the following elements was inserted into the Gt(ROSA)26Sor locus: CAG promoter, a FRT site, a neomycin resistance gene cassette, a STOP cassette, a FRT site, the constitutionally active mutant form of simian TGFB1 cDNA containing the two point mutations C223S/C225S (TGFβCA), IRES sequence, the eYFP fluorescent reporter gene, and bGH poly(A) sequence. The inserted TGFβCA gene and the reporter gene will only be expressed after removal of the neo-STOP cassette through flp-mediated recombination. |
