| Primary Identifier | MGI:6758222 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Prkn |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Most of exon 2 was replaced in-frame by the coding sequence of tau (Mapt) and green fluorescent protein (GFP), followed by translation and transcription termination sequences and the MC1-neomycin cassette. Western blot analysis confirmed the absence of protein in the brain. RT-PCR confirmed the presence of GFP transcripts, however the parkin-tau-GFP fusion protein is not clearly detectable by Western blot or immunohistochemical analysis. |
