Primary Identifier | MGI:6724075 | Allele Type | Targeted |
Attribute String | Inducible, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Inheritance Mode | Not Specified | Transmission | Germline |
Strain of Origin | 129S4/SvJaeSor | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The tetO tetracycline responsive element followed by cDNA sequence coding for the zinc and ring finger 3 extracellular domain were inserted into exon 1 of the locus. The CAG promoter followed by the rtTA16 transactivator cDNA was inserted into intron 1 in the reverse transcriptional direction. This allele expresses the Znrf3 sequence in the presence of doxycycline. |