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Allele : Gt(ROSA)26Sor<tm10(tetO-Znrf3,CAG-rtTA)Npa> gene trap ROSA 26, Philippe Soriano; targeted mutation 10, Novartis Pharma AG

Primary Identifier  MGI:6724075 Allele Type  Targeted
Attribute String  Inducible, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Inheritance Mode  Not Specified Transmission  Germline
Strain of Origin  129S4/SvJaeSor Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The tetO tetracycline responsive element followed by cDNA sequence coding for the zinc and ring finger 3 extracellular domain were inserted into exon 1 of the locus. The CAG promoter followed by the rtTA16 transactivator cDNA was inserted into intron 1 in the reverse transcriptional direction. This allele expresses the Znrf3 sequence in the presence of doxycycline.
  • mutations:
  • Insertion
  • synonyms:
  • Znrf3ECD,
  • Znrf3ECD
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories