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Allele : Flt3<em2(dre/ERT2)Smoc> FMS-like tyrosine kinase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center

Primary Identifier	MGI:6724245	Allele Type	Endonuclease-mediated
Attribute String	Inducible, Recombinase	Gene	Flt3
Strain of Origin	C57BL/6JSmoc	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

description	tamoxifen
molecularNote	A 2A-DreERT2 expression cassette was knocked into the Flt3 gene stop codon site via CRISPR/Cas mediated recombination.

mutations:
Insertion

synonyms:
Flt3<em2(2A-DreERT2)Smoc>,
Flt3-2A-DreER,
Flt3<em2(2A-DreERT2)Smoc>,
Flt3-2A-DreER

earliestPublication:
Han X, et al. (2021) A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

3 Publication categories

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