| Help | About | Contact Us

Allele : Ins2<em2(dre/ERT2)Smoc> insulin II; endonuclease-mediated mutation 2, Shanghai Model Organisms Center

Primary Identifier	MGI:6724254	Allele Type	Endonuclease-mediated
Attribute String	Inducible, Recombinase	Gene	Ins2
Strain of Origin	C57BL/6JSmoc	Induced With	tamoxifen
Is Recombinase	true	Is Wild Type	false

molecularNote

A DreERT2-Wpre-polyA expression cassette was knocked into the initiation codon ATG site of the Ins2 gene via CRISPR/Cas mediated recombination.

mutations:
Insertion

synonyms:
Ins2<em2(DreERT2-Wpre-polyA)Smoc>,
Ins2<em2(DreERT2-Wpre-polyA)Smoc>

earliestPublication:
Han X, et al. (2021) A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

3 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76710238

MouseMine