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Allele : Isl1<em3(dre)Smoc> ISL1 transcription factor, LIM/homeodomain; endonuclease-mediated mutation 3, Shanghai Model Organisms Center

Primary Identifier	MGI:6724258	Allele Type	Endonuclease-mediated
Attribute String	Recombinase	Gene	Isl1
Strain of Origin	C57BL/6JSmoc	Is Recombinase	true
Is Wild Type	false

molecularNote

A Dre-Wpre-polyA expression cassette was knocked into the Isl1 gene start codon site via CRISPR/Cas9 mediated recombination.

mutations:
Insertion

synonyms:
Isl1-Dre,
Isl1<em1(Dre-Wpre-polyA)Smoc>,
Isl1<em1(Dre-Wpre-polyA)Smoc>,
Isl1-Dre

earliestPublication:
Han X, et al. (2021) A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

3 Publication categories

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