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Allele : Trp53bp1<tm1.1Nus> transformation related protein 53 binding protein 1; targeted mutation 1.1, Andre Nussenzweig

Primary Identifier  MGI:6763420 Allele Type  Targeted
Gene  Trp53bp1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A T-to-G mutation was engineered in exon 2 to change serine codon 30 (TCT) to an alanine codon (GCT)(p.S30A), making that residue unphosphorylatable in the encoded peptide. The loxP site flanked neomycin resistance gene that was inserted into intron 1 was removed through subsequent cre-mediated recombination.
  • mutations:
  • Single point mutation
  • synonyms:
  • 53BP1<S25A>,
  • 53BP1<S25A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories