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Allele : Cx3cr1<em1(icre)Smoc> C-X3-C motif chemokine receptor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center

Primary Identifier	MGI:6724386	Allele Type	Endonuclease-mediated
Attribute String	Null/knockout, Recombinase	Gene	Cx3cr1
Strain of Origin	C57BL/6JSmoc	Is Recombinase	true
Is Wild Type	false

molecularNote

The coding region of the Cx3cr1 gene was replaced by a iCre expression cassette via CRISPR/Cas9 mediated recombination.

mutations:
Insertion

synonyms:
Cx3cr1-Cre,
Cx3cr1-Cre,
Cx3cr1<em1(iCre)Smoc>,
Cx3cr1<em1(iCre)Smoc>

earliestPublication:
Yang L, et al. (2021) Depression-like behavior associated with E/I imbalance of mPFC and amygdala without TRPC channels in mice of knockout IL-10 from microglia. Brain Behav Immun

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

5 Publication categories

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