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Allele : Cnr1<tm1.1Mars> cannabinoid receptor 1; targeted mutation 1.1, Giovanni Marsicano
Primary Identifier  MGI:6750932 Allele Type  Targeted
Gene  Cnr1 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  A loxP flanked STOP cassette and Cnr1 sequence lacking the first 22 amino acids replaced the wild-type coding sequence. Cre-mediated recombination excised the STOP cassette. qRT-PCR and immunofluorescence shows no differences in mRNA and protein expression in different brain regions, however the density of mitochondria-associated protein is reduced.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • DN22-CB1-KI,
  • DN22-CB1-KI
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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6 Publication categories

Trail: Allele




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