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Allele : Adra1a<em1Pcs> adrenergic receptor, alpha 1a; endonuclease-mediated mutation 1, Paul C Simpson
Primary Identifier  MGI:6725091 Allele Type  Endonuclease-mediated
Gene  Adra1a Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology was used to generate a 6 amino acid substitution at amino acids 228-233, DSEQVT to CCPGCC, in the third intracellular loop. This change disrupts Gq signaling.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • GqKI,
  • GqKI
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Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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