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Allele : Eif4b<tm1.1Smoc> eukaryotic translation initiation factor 4B; targeted mutation 1.1, Shanghai Model Organisms Center

Primary Identifier	MGI:6790235	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Eif4b
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

Exons 3 and 4 were flanked by loxP sites and an FRT-flanked neomycin cassette was inserted downstream of exon 4. The neomycin cassette was removed via flp-mediated recombination.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
eIF4B<f>,
eIF4B<f>

earliestPublication:
Chen B, et al. (2021) Deficiency of eIF4B Increases Mouse Mortality and Impairs Antiviral Immunity. Front Immunol 12:723885

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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